LMO2

Rhombotin-2 (lim domain only protein 2) (lmo-2)

Reviewed UniProt entries for LMO2 and its protein partners


UniProt code UniProt Name Protein Name Gene Name Organism Length
Q1LZ94 RBTN2_BOVIN Rhombotin-2 (LIM domain only protein 2) (LMO-2) LMO2 RBTN2 Bos taurus (Bovine) 158
Q9PTJ3 RBTN2_DANRE Rhombotin-2 (LIM domain only protein 2) (LMO-2) (zlmo2) lmo2 si:dkey-10o6.5 Danio rerio (Zebrafish) (Brachydanio rerio) 159
P25791 RBTN2_HUMAN Rhombotin-2 (Cysteine-rich protein TTG-2) (LIM domain only protein 2) (LMO-2) (T-cell translocation protein 2) LMO2 RBTN2 RBTNL1 RHOM2 TTG2 Homo sapiens (Human) 158
P25801 RBTN2_MOUSE Rhombotin-2 (Cysteine-rich protein TTG-2) (LIM domain only protein 2) (LMO-2) (T-cell translocation protein 2) Lmo2 Rbtn-2 Rbtn2 Rhom-2 Mus musculus (Mouse) 158
Q90XH3 RBTN2_XENLA Rhombotin-2 (LIM domain only protein 2) (LMO-2) (Lmo2-A) (xLMO-2) lmo2 lmo2-a Xenopus laevis (African clawed frog) 158
Q5M8V8 RBTN2_XENTR Rhombotin-2 (LIM domain only protein 2) (LMO-2) lmo2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) 158

Our searches have not found small molecules for this target yet


6 PDB entries for LMO2 and its protein partners


1J2O
Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4

Entity type Code Description
polypeptide(L) P25801 Fusion of Rhombotin-2 and LIM domain-binding protein 1
polypeptide(L) P70662 Fusion of Rhombotin-2 and LIM domain-binding protein 1

2LXD
Solution structure of a tethered Lmo2(LIM2) /Ldb1(LID) complex

Entity type Code Description
polypeptide(L) P25801 Rhombotin-2, LINKER, LIM domain-binding protein 1
polypeptide(L) 2LXD Rhombotin-2, LINKER, LIM domain-binding protein 1
polypeptide(L) P70662 Rhombotin-2, LINKER, LIM domain-binding protein 1

2XJY
Structure of the Leukemia Oncogene Lmo2: Implications for the Assembly of a Hematopoietic Transcription Factor Complex.

Entity type Code Description
polypeptide(L) P25791 RHOMBOTIN-2
polypeptide(L) Q86U70 LIM DOMAIN-BINDING PROTEIN 1

2XJZ
Structure of the Leukemia Oncogene Lmo2: Implications for the Assembly of a Hematopoietic Transcription Factor Complex.

Entity type Code Description
polypeptide(L) P25791 RHOMBOTIN-2
polypeptide(L) Q86U70 LIM DOMAIN-BINDING PROTEIN 1

2YPA
Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.

Entity type Code Description
polypeptide(L) P17542 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1
polypeptide(L) P15923 TRANSCRIPTION FACTOR E2-ALPHA
polypeptide(L) P25791 RHOMBOTIN-2
polypeptide(L) Q86U70 LIM DOMAIN-BINDING PROTEIN 1
polydeoxyribonucleotide 2YPA EBOX FORWARD
polydeoxyribonucleotide 2YPA EBOX REVERSE

4DOU
Crystal structure of a single-chain trimer of human adiponectin globular domain.

Entity type Code Description
polypeptide(L) P25801 Adiponectin
polypeptide(L) P25801 Adiponectin
polypeptide(L) P25801 Adiponectin