Max

Protein max (myc-associated factor x

Reviewed UniProt entries for Max and its protein partners


UniProt code UniProt Name Protein Name Gene Name Organism Length
P52162 MAX_CHICK Protein max (Myc-associated factor X) MAX Gallus gallus (Chicken) 160
P52161 MAX_DANRE Protein max (Myc-associated factor X) max Danio rerio (Zebrafish) (Brachydanio rerio) 165
P91664 MAX_DROME Protein max (dMax) (Myc-associated factor X) Max CG9648 Drosophila melanogaster (Fruit fly) 161
P61245 MAX_FELCA Protein max (Myc-associated factor X) MAX Felis catus (Cat) (Felis silvestris catus) 160
P28574 MAX_MOUSE Protein max (Myc-associated factor X) (Myc-binding novel HLH/LZ protein) (Protein myn) Max Myn Mus musculus (Mouse) 160
P52164 MAX_RAT Protein max (Myc-associated factor X) Max Rattus norvegicus (Rat) 160
Q07016 MAX_XENLA Protein max (xMAX) (Myc-associated factor X) max Xenopus laevis (African clawed frog) 163
P61244 MAX_HUMAN Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X) MAX BHLHD4 Homo sapiens (Human) 160

Our searches have not found small molecules for this target yet


8 PDB entries for Max and its protein partners


1A93
Insights into the mechanism of heterodimerization from the 1H-NMR solution structure of the c-Myc-Max heterodimeric leucine zipper.

Entity type Code Description
polypeptide(L) P01106 MYC PROTO-ONCOGENE PROTEIN
polypeptide(L) P28574 MAX PROTEIN

1AN2
Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain.

Entity type Code Description
polydeoxyribonucleotide 1AN2 DNA (5'-D(*GP*TP*GP*TP*AP*GP*GP*TP*CP*AP*CP*GP*TP*GP*AP*CP*C P*TP*AP*CP*AP*C)- 3')
polypeptide(L) P61244 PROTEIN (TRANSCRIPTION FACTOR MAX (TF MAX))

1HLO
The crystal structure of an intact human Max-DNA complex: new insights into mechanisms of transcriptional control.

Entity type Code Description
polydeoxyribonucleotide 1HLO DNA (5'-D(*CP*AP*CP*CP*AP*CP*GP*TP*GP*GP*T)-3')
polydeoxyribonucleotide 1HLO DNA (5'-D(*AP*CP*CP*AP*CP*GP*TP*GP*GP*TP*G)-3')
polypeptide(L) P61244 PROTEIN (TRANSCRIPTION FACTOR MAX)

1NKP
X-ray structures of Myc-Max and Mad-Max recognizing DNA: Molecular bases of regulation by proto-oncogenic transcription factors

Entity type Code Description
polydeoxyribonucleotide 1NKP 5'-D(*CP*GP*AP*GP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*CP*TP*C)-3'
polypeptide(L) P01106 Myc proto-oncogene protein
polypeptide(L) P61244 Max protein

1NLW
X-ray structures of Myc-Max and Mad-Max recognizing DNA: Molecular bases of regulation by proto-oncogenic transcription factors

Entity type Code Description
polydeoxyribonucleotide 1NLW 5'-D(*GP*AP*GP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*CP*TP*C)-3'
polypeptide(L) Q05195 MAD PROTEIN
polypeptide(L) P61244 MAX PROTEIN

1R05
The NMR solution structure of a mutant of the Max b/HLH/LZ free of DNA: insights into the specific and reversible DNA binding mechanism of dimeric transcription factors

Entity type Code Description
polypeptide(L) P61244 Max protein

2A93
Insights into the mechanism of heterodimerization from the 1H-NMR solution structure of the c-Myc-Max heterodimeric leucine zipper.

Entity type Code Description
polypeptide(L) P01106 C-MYC-MAX HETERODIMERIC LEUCINE ZIPPER
polypeptide(L) P28574 C-MYC-MAX HETERODIMERIC LEUCINE ZIPPER

3U5V
Crystal structure of the minimalist max-e47 protein chimera.

Entity type Code Description
polypeptide(L) P28574 Protein max, Transcription factor E2-alpha chimera
polypeptide(L) P15923 Protein max, Transcription factor E2-alpha chimera